Presentation and surgical management approaches of giant presacral and sacral schwannomas: a case report and systematic review and meta-analysis.

Background: Giant sacral and presacral schwannomas are very rare conditions and their prevalence is estimated to account for only 0.3 to 3.3% of overall schwannomas.

Mini-open transosseous repair with bursal augmentation improves outcomes in massive rotator cuff tears.

Treatment of Massive rotator cuff tears (MRCT) is difficult, with high rates of retears. Using biological augmentation in the form of the highly vascular subacromial bursa, was used to improve tendon healing. This work aimed to evaluate the results of arthroscopic guided mini-open transosseous repair with bursal augmentation in the treatment of MRCTs in a five-step approach.

Urinary congophilia as a predictive biomarker of lupus nephritis in pregnant and non-pregnant women with systemic lupus erythematosus.

Background: Endoplasmic reticulum stress with protein misfolding has been introduced as a key pathogenetic mechanism in lupus nephritis (LN). Pregnancy is thought to exaggerate proteostasis, which leads to the accumulation of potentially pathogenic misfolded proteins in the urine, serum, and placenta particularly in women with preeclampsia. The detection of misfolded proteins is made using Congo red stain, which is referred to as congophilia.

Endosinotarsal vs. Exosinotarsal Subtalar Arthroereisis in Treating Pediatric Flexible Flat Feet: A Systematic Review and Meta-Analysis of Comparative Studies.

Background: Pediatric flexible flatfoot (FFF) is a common condition characterized by the collapse of the medial longitudinal arch, which can lead to pain and functional impairment in a subset of patients. Subtalar arthroereisis (AR) is a minimally invasive procedure that corrects FFF by limiting excessive pronation of the subtalar joint. Two main techniques exist: endosinotarsal AR, which involves placing an implant in the sinus tarsi, and exosinotarsal AR, which uses a screw external to the sinus tarsi.