Identifying the Function of Kinesin Superfamily Proteins in Gastric Cancer: Implications for Signal Transduction, Clinical Significance, and Potential Therapeutic Approaches.

Gastric cancer (GC), a leading cause of cancer-related mortality, poses a significant global health challenge. Given its complex etiology, understanding the molecular pathways driving GC progression is crucial for developing innovative therapeutic strategies. Among the diverse proteins involved in cellular transport and mitotic regulation, kinesin superfamily proteins (KIFs) have emerged as key players in tumor biology.

KIFC1 in Cancer: Understanding Its Expression, Regulation, and Therapeutic Potential.

Kinesins are a family of motor proteins essential for intracellular transport and cellular dynamics, with kinesin family member C1 (KIFC1) emerging as a key regulator of cancer progression. Recent studies highlight KIFC1's crucial role in mitotic spindle assembly, chromosome segregation, and cell migration-processes frequently dysregulated in cancer. Its involvement in promoting malignant cell proliferation and metastasis underscores its significance in tumor biology.

Computational investigation of graphyne monolayer as a promising carrier for anticancer drug delivery.

The study employs density functional theory (DFT) to examine the drug-loading efficiency of graphyne (GYN) as a vehicle for the Tioguanine (TG) drug. The researchers analyzed the interaction energy, electrical properties of pure GYN, TG molecules, and TG@GYN complex to determine their effectiveness as a carrier. Configuration a, which utilized nitrogen and sulfur atoms in interactions, was deemed the most suitable among the three considered TG sites.

Monitoring indoor air quality using smart integrated gas sensor module (IGSM) for improving health in COPD patients.

Technology advancement, industrialisation, and globalisation have been significant reasons for air pollution outdoors and indoors. It may surprise us that we spend about 80% of our time indoors breathing toxic, stale, polluted air, making us sluggish and fretful. In contrast to outdoor air, indoor air does not recycle consistently.

Energetic Glaucoma Segmentation and Classification Strategies Using Depth Optimized Machine Learning Strategies.

Glaucoma is a major threatening cause, in which it affects the optical nerve to lead to a permanent blindness to individuals. The major causes of Glaucoma are high pressure to eyes, family history, irregular sleeping habits, and so on. These kinds of causes lead to Glaucoma easily, and the effect of such disease leads to heavy damage to the internal optic nervous system and the affected person will get permanent blindness within few months.