Publications by authors named "A STOENESCU"
Introduction Chronic hepatitis C (CHC) remains a significant public health concern due to both hepatic and extrahepatic manifestations associated with substantial morbidity and mortality. The emergence of SARS-CoV-2 has raised concerns about the outcomes of COVID-19 in CHC patients. Method We conducted a retrospective analysis of patients with CHC and SARS-CoV-2 infection admitted to a tertiary care hospital between 2020 and 2023.
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- - Hepatitis C virus (HCV) can affect not just the liver but also other tissues, leading to conditions like cryoglobulinemia, lymphoproliferative diseases, metabolic disorders, and neuropsychiatric issues due to immune responses triggered by the virus.
- - The immune response to HCV contributes to these extrahepatic manifestations, showing that the virus has far-reaching effects beyond liver damage.
- - Antiviral therapies that target HCV help alleviate these extrahepatic issues, improve patients' quality of life, and address HCV as a significant public health concern.
Article Synopsis
- Acute insulin resistance and hyperglycemia are common during acute myocardial infarction (AMI) and can worsen patient outcomes, regardless of whether the patient has diabetes.
- Neutrophilia, which is the increased presence of neutrophils in the blood, is linked to poor prognosis in AMI cases, and its relationship with stress-induced hyperglycemia and insulin resistance needs further exploration.
- A study conducted on 219 AMI patients examined the effects of these metabolic disturbances on inflammatory markers and found that those with stress hyperglycemia generally had worse prognoses.
Introduction Chronic hepatitis C virus (HCV) infection is associated with various extrahepatic manifestations, including depression. This study aimed to determine the prevalence of depression in treatment-naive HCV patients and explore its potential association with liver fibrosis severity. Methodology A consecutive cohort of 50 treatment-naive HCV patients without coinfections was enrolled over six months.
View Article and Find Full Text PDFThe Elevated Inflammatory Status of Neutrophils Is Related to In-Hospital Complications in Patients with Acute Coronary Syndrome and Has Important Prognosis Value for Diabetic Patients.
Int J Mol Sci
May 2024
Despite neutrophil involvement in inflammation and tissue repair, little is understood about their inflammatory status in acute coronary syndrome (ACS) patients with poor outcomes. Hence, we investigated the potential correlation between neutrophil inflammatory markers and the prognosis of ACS patients with/without diabetes and explored whether neutrophils demonstrate a unique inflammatory phenotype in patients experiencing an adverse in-hospital outcome. The study enrolled 229 ACS patients with or without diabetes.
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