Publications by authors named "A SCHERRER"

Purpose: Prospective, multicentric observational cohort study in Switzerland investigating measures to prevent mother-to-child transmission in pregnant women with HIV (WWH) and assessing health and development of their exposed children as well as of children with HIV (CWH) in general.

Participants: Between January 1986 and December 2022, a total of 1446 mother-child pairs were enrolled. During the same period, the study also registered 187 CWH and 521 HIV-exposed but uninfected children (HEU), for whom detailed maternal information was not available.

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Aims: This study evaluated an approach to establishing a comprehensive nationwide surveillance system for Clostridioides difficile infection in Switzerland. We report the results of patient-related surveillance and calculate the incidence rate of C. difficile infection in Switzerland in 2022.

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Background: Hospital-acquired pneumonia (HAP) and its specific subset, non-ventilator hospital-acquired pneumonia (nvHAP) are significant contributors to patient morbidity and mortality. Automated surveillance systems for these healthcare-associated infections have emerged as a potentially beneficial replacement for manual surveillance. This systematic review aims to synthesise the existing literature on the characteristics and performance of automated nvHAP and HAP surveillance systems.

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Article Synopsis
  • Intravascular catheters are vital in medicine but increase the risk of healthcare-associated infections (HAIs), prompting a review of automated algorithms for detecting catheter-related bloodstream infections (CRBSI) and central line-associated bloodstream infections (CLABSI).
  • A systematic literature search from 2000 to 2021 led to 9 studies being included that evaluated the performance of these algorithms, focusing mainly on CLABSI detection and utilizing various types of data.
  • The findings highlighted a lack of uniformity among the automated systems, with diverse definitions and methodologies, suggesting the need for more standardized approaches to improve infection surveillance in healthcare settings.
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Background: Intravascular catheter infections are associated with adverse clinical outcomes. However, a significant proportion of these infections are preventable. Evaluations of the performance of automated surveillance systems for adequate monitoring of central-line associated bloodstream infection (CLABSI) or catheter-related bloodstream infection (CRBSI) are limited.

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