The Impact of Patient Adherence to Dual Antiplatelet Medication Following Percutaneous Coronary Intervention on the Occurrence of Adverse Cardiovascular Events.

Background: The objective of this study is to examine the impact of medication adherence on the timing of non-cardiovascular serious events (NCDS) onset in patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI).

Methods: This prospective study was conducted at a single center and involved 220 ACS patients who underwent sequential PCI with stenting. The Morisky Green Levine Medication Adherence Scale was employed to assess adherence to dual antiplatelet therapy (DAPT) and its impact on NCDS occurrence.

Independent predictors of acute kidney injury in patients with acute coronary syndrome after percutaneous coronary intervention.

Introduction: High residual platelet reactivity (RPR) in patients after percutaneous coronary intervention (PCI) receiving antiplatelet agents has been associated with a high risk of developing acute kidney injury (AKI).

Study Aim: This study aimed at identification of independent prognostic predictors of AKI risk in patients with acute coronary syndrome (ACS) after PCI.

Study Design, Setting And Patients: This was a prospective single-center clinical trial that included 155 patients (n = 119 without AKI, n = 36 with AKI, mean age 64.

[Reference values of platelet aggregometry in healthy subjects.].

In this article, we set forth the average values and reference intervals of platelet aggregation in practically healthy individuals on the AggRAM optical aggregometer. The reference intervals of platelet aggregation activity with 5 µg/ml adenosine-5`-diphosphate and the area under the aggregation curve were 67,4-92,5% and 54,5-85,3; the reference intervals of platelet activity with 10 µg/ml adenosine-5`-diphosphate and the area under the aggregation curve were 76,8-97,2%% and 68,8-90,4. The obtained values of indicators can be used as reference in the clinical diagnostic laboratory of the University Hospital of Semey State Medical University.