Publications by authors named "A S Wexler"
Substance use disorders (SUDs) are a significant public health concern, with over 30% failing available treatment. Severe SUD is characterized by drug-cue reactivity that predicts treatment-failure. We leveraged this pathophysiological feature to personalize deep brain stimulation (DBS) of the nucleus accumbens region (NAc) in an SUD patient.
View Article and Find Full Text PDFThe small splice variant of the sulfonylurea receptor protein isoform 2 A (SUR2A-55) targets mitochondria and enhances mitoK activity. In male mice the overexpression of this protein promotes cardioprotection, reducing myocardial injury after an ischemic insult. However, it is unclear what impact SUR2A-55 overexpression has on the female myocardium.
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- Wildfire smoke can affect grape composition, leading to the production of "smoke tainted" wines due to increased volatile phenols (VPs) in the grapes and wines.
- A study used passive samplers to measure smoke exposure on Cabernet Sauvignon grapes and found a strong correlation between smoke intensity and VPs levels in both grapes and wines.
- The passive samplers showed an impressive accuracy in predicting guaiacol concentrations, indicating their potential use as a monitoring tool for vineyards during smoke events.