Publications by authors named "A S Wenning"
Orofacial clefts are among the most prevalent birth defects, with severe medical and psychosocial consequences. Cleft lip with or without cleft palate (CL ± P) and cleft palate only (CPO) affect on average nearly 1/700 births worldwide. The cause of most non-syndromic cases is unknown.
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- A systematic review and meta-analysis assessed how accurately Artificial Intelligence (AI) diagnoses approximal carious lesions on bitewing radiographs, using data from multiple controlled trials.
- Out of 2,442 studies, 21 met criteria, revealing AI's pooled sensitivity at 0.94 and specificity at 0.91, indicating it is good at finding caries and excluding healthy teeth.
- While AI shows promise in initial screening for caries detection, dental professionals should confirm positive findings to avoid unnecessary treatments and ensure accurate diagnosis.
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- Researchers wanted to see if a new method called fully closed-loop (FCL) glucose control is better and safer than the usual way (UC) for managing high blood sugar in surgery patients.
- In a study with 37 patients, those using FCL spent more time in a healthy blood sugar range (80.1%) compared to those using UC (53.7%).
- The FCL method helped control high blood sugar without causing low blood sugar, proving to be a safe and effective way for patients during and after surgery.
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- The study investigates the differences between high-immunogenic (HI-PDAC) and low-immunogenic (LI-PDAC) pancreatic ductal adenocarcinoma (PDAC) tumors, focusing on how the immune environment affects their responses to treatments.
- Using spatial proteomic and transcriptomic analyses from 220 PDAC patients, researchers discovered that HI-PDAC tumors have more immune-active environments with higher levels of T-cells and immune-related markers compared to LI-PDAC tumors, which display immune evasion.
- The findings suggest that HI-PDAC patients tend to have better outcomes but also show signs of immune exhaustion, indicating that understanding these immune dynamics could help improve treatment strategies for PDAC, particularly with immune checkpoint therapies.
Outcome prediction in prolonged disorders of consciousness (DOC) remains challenging. This can result in either inappropriate withdrawal of treatment or unnecessary prolongation of treatment. Electroencephalography (EEG) is a cheap, portable, and non-invasive device with various opportunities for complex signal analysis.
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