Publications by authors named "A S Vlasov"
Adenosine triphosphate (ATP) synthases are large enzymes present in every living cell. They consist of a transmembrane and a soluble domain, each comprising multiple subunits. The transmembrane part contains an oligomeric rotor ring (c-ring), whose stoichiometry defines the ratio between the number of synthesized ATP molecules and the number of ions transported through the membrane.
View Article and Find Full Text PDFCarbapenem-resistant (CRE) are a global health threat due to their high morbidity and mortality rates and limited treatment options. This study examines the plasmid-mediated transmission of virulence and antibiotic resistance determinants in carbapenem-resistant () and () isolated from Russian hospitals. : We performed short- and long-read whole-genome sequencing of 53 clinical isolates (48 and 5 ) attributed to 15 genetic lineages and collected from 21 hospitals across nine Russian cities between 2016 and 2022.
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- Ferritin-based hybrids are large macromolecules with potential uses in drug delivery and vaccines, but their design is complicated.
- Researchers designed hybrids using ferritin from Helicobacter pylori and a Small Ubiquitin-like Modifier, discovering that their assembly was influenced by varying preparation methods.
- They developed a quantitative model to analyze how different stoichiometries affected the structure of these hybrids, revealing unexpected patterns and establishing a framework for better design of ferritin-based systems.
Unlabelled: The first maxillary molar is one of the most difficult teeth for endodontical treatment; it presents the highest failure rates due to the impossibility of locating and treating the second mesiobuccal canal (MB2). The aim of our work was study of second mesiobuccal canal in maxillary first molar and compare obtained data with literature sources for increasing the efficiency of treatment.
Materials And Methods: The study involved 59 patients with exacerbation of chronic pulpitis or chronic periodontitis who were distributed according to age: 14-20 years, 21-30 years and 31-40 years.
One of the promising drug delivery tools is ferritin, which features high stability at a wide range of conditions and protects cargo by its spherical protein shell. We studied the self-assembly into homoglobules of ferritin from H. pylori and a chimeric protein ferritin-SUMO.
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