In vitro activity of ampicillin, cefoperazone, their combinations with sulbactam and other antimicrobials: survey of Russian isolates.

Methodological differences makes it difficult to compare results of antimicrobial susceptibility testing obtained in Russia and in other regions. During the period from October 1993 to May 1994 susceptibility of 1296 isolates of bacteria was investigated according to NCCLS standards by the broth microdilution method. The order of activity of antibiotics against Gram-negative bacteria based on percent of susceptible strains from common hospitals were: amikacin (98%) > ciprofloxacin (93%) = imipenem (93%) > cefoperazone/sulbactam (92%) > ceftazidime (89%) > ceftriaxone (81%) > cefotaxime (80%) > cefoperazone (77%) > gentamicin (71%) > ampicillin/sulbactam (51%) > cefazoline (45%) > ampicillin (25%).