Unlabelled: Atherosclerosis has lead to lower limbs chronic occlusive arterial disease in 80-90 % of cases. The progress of atherosclerosis is vascular wall self-regulation process violation, and its correction can be made by completion of missing endogenous peptides.
Objective: assessment of the possibility to use the vasoactive peptid of Vezugen as monotherapy in patients underwent surgery for chronic lower limbs ischemia.