Publications by authors named "A S SARATIKOV"

For people ill with benign hypertension and going through basis hypotensive therapy, taking in Siberian pine nut oil as much as 17,5 g per day, is accompanied by cholesterol-lessening effect, normalization of lipid spectrum of blood, systolic (maximum) benign pressure and lessening of surplus body mass.

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Polyphenolic complexes (PPCs) extracted from core wood and cell culture of Maackia amurensis decrease the acute toxicity of tetrachloromethane, suppress the necrosis of hepatocytes and the cellular infiltration in liver parenchyma, prevent the development of fatty and protein dystrophy in the liver, normalize the activity of aminotransferases and gamma-glutamyltransferase in the blood, restore the protein and lipid content, and stimulate the conjugation of bilirubin. The therapeutic effect was more pronounced for the PPC obtained from the cell culture. The hepatoprotector effect of the PPCs is due to the presence of isoflavonoids, including daidzein, retusin, genistein, afromosin, formononetin, orobol, tektorigenin, maakiain, and medicarpin.

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The results of experiments on white rats with CCl4-induced hepatitis showed that the combined introduction of cyclophosphamide and hepatoprotectors of the plant origin (lochein, maksar, silimarin) leads to a decrease in acute toxicity and to less pronounced manifestations of hepatotoxicity of cyclophosphamide. Hepatoprotectors decrease the activity of aminotransferases, reduce the level of bilirubin, normalize the content of protein andpipids in the blood serum, and suppress the development of morphological disorders in the liver.

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Aim: To examine clinical efficacy of combined therapy with reaferon and iodantipirin in patients with chronic hepatitis B and C of moderate activity.

Material And Methods: 100 patients with confirmed diagnosis of chronic viral hepatitis (CVH) at the stage of replication. All the patients have undergone puncture biopsy of the liver with estimation of index of histological activity Knodell and index of fibrosis Desmeth.

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The paper provides evidence for that as compared with the well-known drug carsil, the new Russian phytohepatoprotective agent maxar has a therapeutic efficiency in patients with mild and moderate chronic hepatitis (CH) of viral and alcoholic etiology. Maxar has been found to produce a more pronounced hepatoprotective effect, to a greater extent, in CH of alcoholic etiology.

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