Increased light scatter in simulated cataracts degrades speed perception.

Changes in contrast and blur affect speed perception, raising the question of whether natural changes in the eye (e.g., cataract) that induce light scatter may affect motion perception.

Evaluation of medication appropriateness index in cardiovascular outpatient clinic: A cross-sectional study.

Background: Older adults often have polypharmacy and multimorbidity. Cardiovascular diseases (CVDs) are the most common multimorbidities in older adults and are linked to wide range of adverse drug effects and drug-related problems. The medication appropriateness index (MAI) has been widely used in several patient settings to assess Potentially Inappropriate Medication (PIM) prescribing in older adults.

Cilostazol geno-protective effects mitigate carbamazepine-induced genotoxicity in human cultured blood lymphocytes.

Background: Carbamazepine is one of the most widely used antiepileptic drugs. Carbamazepine has been shown to be toxic to cells. Cilostazol, an antiplatelet agent, has known antioxidant, antiproliferative, anti-inflammatory, and anti-tumor effects.

Pentoxifylline protects memory performance in streptozotocin-induced diabetic rats.

Diabetes, characterized by elevated blood glucose levels and associated organ damage, is reportedly correlated with adecline in cognitive functions with a potential involvement of oxidative stress mechanisms. Mitochondria-induced oxidative stress reported to cause hyperglycemia is believed to impair hippocampal neural plasticity, affecting long-term potentiation, and isconsidered crucial for maintaining memory functions. In this study, the neuroprotective effect of Pentoxifylline (PTX) for four weeks, an agent known for antioxidant and anti-inflammatory properties, was examined in an animal model of diabetes.

Evaluation of five methods for the interpolation of bad leads in the solution of the inverse electrocardiography problem.

This study aims to assess the sensitivity of epicardial potential-based electrocardiographic imaging (ECGI) to the removal or interpolation of bad leads.We utilized experimental data from two distinct centers. Langendorff-perfused pig (= 2) and dog (= 2) hearts were suspended in a human torso-shaped tank and paced from the ventricles.