Publications by authors named "A S Proia"
A woman in her early 20s underwent excision of a 6-mm diameter, tender, mobile mass in the temporal left upper eyelid associated with eyelid swelling and blurred vision. Surgery disclosed a large tarsal lesion that appeared to be a cyst but was found to be a soft-tissue chondroma featuring an island of hyaline cartilage surrounded by dense tarsal fibrous connective tissue containing smaller foci of myxoid cartilage. The woman reported that a nodule had been present at this site since childhood.
View Article and Find Full Text PDFDermoid Cyst of Conjunctival Origin Attached to the Tarsus in a Pediatric Patient.
Ophthalmic Plast Reconstr Surg
December 2024
Dermoid cysts of cutaneous origin are common orbital lesions, whereas dermoid cysts of conjunctival origin are rare. The authors present a case of a dermoid cyst of conjunctival origin that was attached to the tarsus in a pediatric patient. A 2-year-old boy presented to the clinic with an approximately 2 cm in diameter mobile nodule in the upper eyelid on the temporal side that distorted the eyelid architecture with temporal ptosis.
View Article and Find Full Text PDFArticle Synopsis
- Outer retinal degenerations like age-related macular degeneration (AMD) involve damage to photoreceptors and retinal pigment epithelium (RPE), with macrophages clustering at these damaged areas, but their roles are not fully understood, especially in humans.
- The study found that a specific group of microglia expressing galectin-3 is active in areas of retinal degeneration, and when galectin-3 was removed, it resulted in more photoreceptor loss and RPE damage, highlighting its protective function.
- Additionally, signals from Trem2 were shown to guide microglial movement to damaged sites and increase galectin-3 expression, suggesting that enhancing this pathway could offer new treatment strategies for retinal degeneration in AMD patients.
Introduction: Emerging evidence suggests a high burden of psychosocial comorbidities in patients with eosinophilic esophagitis (EoE), although factors associated with this burden have not been explored. We aimed to increase understanding of the psychosocial burden of EoE and assess factors that are associated with disease burden.
Methods: We conducted a cross-sectional study of patients with EoE (n = 87) recruited from a single-center, multidisciplinary pediatric eosinophilic gastrointestinal disorders clinic (2019-2021).