[Hemodynamic features during coronary bypass surgery on the working heart].

Changes in hemodynamics and blood oxygen transport function were studied during coronary bypass surgery (CBS) on the working heart under anesthesia with propofol and fentanyl. In patients operated on the working heart, the course of the basic stage of an operation was characterized by a moderate reduction in cardiac index and stroke volume due to the cardiac changes and immobilization, which resulted in cardiac compression and venous return deterioration. These impairments did not lead to worse oxygen-transportfunction and they were completely eliminated in the rehabilitative period.

[Criteria of functional operability and indications for intraoperative volumetric monitoring of patients during extensive surgical procedures on the lung].

The investigation included 32 patients after extensive operative interventions on the lungs: pneumonectomy with circular resection of the trachea bifurcation and different kinds of combined pneumonectomies. Methods of Doppler echocardiography and thermal dilution were used for studying the parameters of lesser circulation before, during and after operation. Patients with the initially impaired hemodynamics had more pronounced functional changes after surgical procedures.

[Cardiac right ventricular function and hemodynamics during resection of the lungs].

Right-ventricular function and hemodynamics were studied in 48 patients during resections of the lungs (lobectomy and pneumonectomy) under total noninhalation anesthesia. Approaches to compensation of circulation in resection of different volume of lung tissue were determined. The leading role of the diastolic function of the right heart ventricle in realization of hemodynamic response in pneumonectomy is revealed.

[Postpneumonectomy syndrome: several new anesthesiological and pathophysiological aspects].

As a result of 10-year investigations a concept of postpneumonectomy syndrome (PPS) has been defined as a combination of acute respiratory disturbances due to alteration of filtration and absorption functions of the lungs along with systolic and diastolic right heart dysfunction. The aim of the study was to identify the details of PPS pathogenesis dependent on the initial right chamber pressure levels and a search for probable approaches to PPS correction. The study was carried out on 26 patients subject to pneumonectomy.