Among flaviviruses, Zika virus (ZIKV) is the only arbovirus officially recognized as a teratogenic agent, as a consequence of its ability to infect and cross the placental barrier causing congenital malformation in the fetus. While many studies have focused on understanding ZIKV pathogenesis during pregnancy, the viral mechanisms affecting fetal development remain largely unclear. In this study, we investigated ZIKV virulence in placental trophoblasts, using viruses with distinct lipid profiles.
View Article and Find Full Text PDFPlant phenotyping on morpho-anatomical traits through image analysis, from microscope images to large-scale acquisitions through remote sensing, represents a low-invasive tool providing insight into physiological and structural trait variation, as well as plant-environment interactions. High phenotype diversity in the genus Amaranthus includes annual weed species with high invasiveness and impact on important summer crops, and nutritive grain or vegetable crops. Identification of morpho-anatomical leaf characters at very young stages across weedy amaranths could be useful for better understanding their performance in agroecosystems.
View Article and Find Full Text PDFRationale: Metastatic castration-resistant prostate cancer has a poor prognosis especially when harboring DNA damage repair gene mutations, nevertheless, in the case of pathogenic BRCA gene mutations, PARPi demonstrated a survival benefit and is a validated treatment. Nowadays, there is no data regarding unusual metastases after these drugs. Cutaneous metastases appear rarely in prostate cancer and were associated with a worse prognosis.
View Article and Find Full Text PDFObjectives: This study aimed to assess the effect of addition of bioactive glass (BG) on the setting time and antibacterial activity of mineral trioxide aggregate (MTA) against Enterococcus faecalis (E. faecalis).
Materials And Methods: In this in vitro study, BG was synthesized by the sol-gel technique and added to MTA powder in certain ratios.
Background: Cardiovascular disease (CVD) is the leading cause of death and disability worldwide, particularly in low- and middle-income countries. Young adults are susceptible to CVD risk factors, especially in developing countries. This study aimed to compare CVD risk factors between medical and non-medical students.
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