[Laparoscopic and open heminephrectomy in children: results comparison].

Unlabelled: Objectives. To compare the results of laparoscopic and open heminephrectomy for kidneys duplication in children. Materials and methods.

Propagation and breakup of liquid menisci and aerosol generation in small airways.

Background: Droplets exhaled during normal breathing and not associated with coughing may pose hazardous agents to infective diseases dissemination. The objective is to explore the physical mechanism, which may lead to droplets formation.

Methods: We hypothesize that liquid menisci occlusions, which may form inside small airways, travel along the airway, may lose mass and finally disintegrate into small droplets.

[The 1xC3 panel of recombinant inbred mouse strains. Presence or absence of pathologic neurologic traits of one of parental strains].

Mice from the earlier developed recombinant inbred strains (RIS), which were derived by crossing 101/HY mice (carrying the mut-1 allele determining increased susceptibility to the mutagenic action of alkylating compounds) with C3H/Sn mice (lacking this trait), were tested for the presence of two neurological pathologies, audiogenic epilepsy and splitting of pyramidal cell layer of the CA3 hippocampal field (specific only to 101/HY mice). It was demonstrated that segregation of RIS relative to these traits was independent from the presence or absence of the mut-1 allele. These findings suggested the appearance of mut-1-independent mutations in the 101/HY mice, which resulted in the development of neurological pathologies.

Localization of green fluorescent protein in mouse preimplantation embryos.

The localization of enhanced green fluorescent protein (EGFP) was studied in preimplantation embryos obtained from reciprocal mating of hemizygous C57Bl/6-Tgn (ACTbEGFP)1Osb/J mice with C57Bl/6 mice. Specific fluorescence of EGFP was observed in all oocytes and embryos obtained from transgenic females during all preimplantation stages and in embryos inheriting the EGFP gene from transgenic males starting from the 8 blastomere stage during the compactization period. EGFP mRNA or EGFP synthesized during oogenesis can be retained in embryos during the entire preimplantation period, while expression of EGFP gene transferred from the father coincides with the onset of compactization.

[The cellular effects of functional unloading and passive stretch on m. soleus of dystrophin-deficient mdx mice].

Dystrophin, subsarcolemmal protein communicating muscle fiber cytoskeleton to extracellular matrix, is believed to participate in mechanical signal transduction. Recent works testify possible signaling role of this protein to prevent development ofproteolytic processes accompanying muscle fiber atrophy and to stimulate the passive stretch anabolic effects. The experiment was carried out to assess the role of dystrophin in these processes.