Publications by authors named "A S Lobacheva"
Article Synopsis
- This study investigates cases of vasculitis in children linked to COVID-19, highlighting a limited but concerning phenomenon.
- Four pediatric cases showed diverse systemic involvement, primarily affecting the skin; while all patients presented with high inflammatory markers, none fully met criteria for multisystem inflammatory syndrome.
- Treatment included systemic glucocorticosteroids, with additional therapies like DMARDs and biologics, underscoring the potential severity of COVID-19-related vasculitis and the need for more comprehensive research.
Some BDNF (brain-derived neurotrophic factor)-targeted microRNAs such as miR-30a-5p associate with alcohol dependence phenomenon however their relationship with AWS is not described. We aimed to measure serum BDNF concentration and relative content of miR-30a-5p over the course of alcohol abstinence and compare obtained results with clinics of AWS. Additionally, we studied relative serum content of miR-30a-5p, a microRNA which does not target BDNF but relates to alcohol use disorder.
View Article and Find Full Text PDFIntroduction And Aim: Polymorphic variant rs738409 within the PNPLA3 gene associates with alcoholic liver cirrhosis (ALC) in heavy drinkers of various ancestry but has not yet been established in the Russian population characterized by high incidence of ALC. PNPLA3 rs738409 involvement in the inflammatory process has been proposed as one of the mechanisms of liver dysfunction. Relationship between the PNPLA3 polymorphism and the biochemical markers of inflammation in patients with ALC remains unclear.
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