Immunotherapies aimed at preserving residual beta cell function in type 1 diabetes have been successful, although the effect has been limited, or raised safety concerns. Transient effects often observed may necessitate redosing to prolong the effect, although this is not always feasible or safe. Treatment with intralymphatic GAD-alum has been shown to be tolerable and safe in persons with type 1 diabetes and has shown significant efficacy to preserve C-peptide with associated clinical benefit in individuals with the human leukocyte antigen DR3DQ2 haplotype.
View Article and Find Full Text PDFBackground: Healthy lifestyle behaviors in pregnancy are important for maternal and offspring health. Mobile health (mHealth) tools have potential to provide support for lifestyle behaviors at scale but such tools are commonly developed only in native languages, limiting reach in migrant populations.
Objectives: This qualitative study, in two of the largest migrant populations in Sweden (Arabic- and Somali-speaking women), aimed to explore (a) perceptions and needs of knowledge and support related to pregnancy and lifestyle behaviors and (b) needs of and attitudes towards a pregnancy app and how features and content in the app can be adapted to support healthier lifestyle behaviors in migrant women.
This paper analyses different modes and cycles of seat vibration in city buses by analysing acceleration peak magnitudes and their trends and fluctuations in the time domain. The purpose is to find peak vibration modes that exist in the driving patterns of city buses. Analysing peaks in a time series is essential for many applications specifically in vibration analysis because they represent significant events.
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