Clinical comparison of cardiorespiratory effects during unilateral and conventional spinal anaesthesia.

Background: Spinal anaesthesia is widely employed in clinical practice but has the main drawback of post-spinal block hypotension. Efforts must therefore continue to be made to obviate this setback

Objective: To evaluate the cardiovascular and respiratory changes during unilateral and conventional spinal anaesthesia.

Methods: With ethical approval, we studied 74 American Society of Anesthesiologists (ASA), physical status class 1 and 2 patients scheduled for elective unilateral lower limb surgery.

Open comparative study of the efficacy, safety and tolerability of midazolam versus thiopental in induction and maintenance of anaesthesia.

In a multicentre study, 145 adult Nigerian patients presenting with diverse conditions (falling into ASA1 or ASA2 classification) for short surgical procedures (< 1 hour) were given either midazolam (0.15-0.20 mg/kg) or thiopentone (4-6 mg/kg) intravenously for induction of anaesthesia.