Publications by authors named "A S Kogan"

Introduction: The World Health Organization global standard for representing drug data is the Anatomical Therapeutic Chemical (ATC) classification. However, it does not represent ingredients and other drug properties required by clinical decision support systems. A mapping to a terminology system that contains this information, like RxNorm, may help fill this gap.

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  • Nutcracker syndrome is a condition where the left renal vein is compressed by the superior mesenteric artery and aorta, potentially causing symptoms like abdominal pain and hematuria.
  • A case study describes a 10-year-old girl who experienced chronic left flank pain for over two years and was diagnosed with Nutcracker syndrome.
  • Her treatment involved surgically moving the left ovarian vein to relieve pressure on the left renal vein, and she has been symptom-free one year post-surgery, highlighting the procedure's effectiveness and low complication rate.
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Immunodetection of cardiac isoforms of troponin I (cTnI) and troponin T (cTnT) in blood samples is widely used for the diagnosis of acute myocardial infarction. The cardiac troponin complex (ITC-complex), comprising cTnI, cTnT, and troponin C (TnC), makes up a large portion of troponins released into the bloodstream after the necrosis of cardiomyocytes. However, the stability of the ITC-complex has not been fully investigated.

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  • The war that started on October 7, 2023, has led to an unexpected rise in open-heart surgeries at Israel's largest cardiac surgery department, despite half of the surgeons being in military service.
  • A study analyzed data from 275 patients who had cardiac surgeries or ECMO during the first two months of the war, comparing it to a similar period in 2022.
  • Results showed a 33% increase in open-heart procedures and a significant rise in transplants in 2023, but patient outcomes, including complications and mortality rates, remained consistent with those from 2022.
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  • Atrial fibrillation (AF) is a common heart rhythm disorder, and this study explores the effectiveness of surgical ablation as a treatment option, especially for patients also undergoing other cardiac surgeries.
  • The research involved 668 patients who underwent this procedure between 2006 and 2022, assessing their outcomes over multiple years, including recurrence of AF and mortality rates.
  • Results showed high success rates for maintaining freedom from AF, with success decreasing slightly over 7 years, while factors like age, female sex, and diabetes were linked to higher risks of recurrence and mortality.
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