The influence of serum uric acid on coronary atherosclerosis plaque phenotypes by computed tomography angiography: The missing link?

Background And Aims: The interaction of serum uric acid (SUA) with atherogenesis is incompletely understood. Aim of our study was to investigate the association of SUA levels with coronary plaque composition including high-risk-plaque (HRP) features by coronary computed tomography angiography (CTA) and for the prediction of major adverse cardiac events (MACE).

Methods And Results: 1242 patients (age 66.

Diagnostic Impact of Subcutaneous Edema in Gouty Feet Detected by Dual-Energy Computed Tomography and Ultrasound.

: The objective of our study was to evaluate the association and frequency of subcutaneous lymphedema in patients with gout primarily affecting the feet. : In 79 patients with acute gout, ultrasound (US) and dual-energy computed tomography (DECT) were performed to assess the presence of subcutaneous edema and extra- and intra-articular gouty deposits. In addition, the diagnostic utility of two post-processing DECT protocols were evaluated, comprising different minimum attenuation thresholds of 150 HU (DECT 150 protocol) and 120 HU (DECT 120 protocol), with the same maximum attenuation threshold (500 HU) and constant kilovoltage setting of tubes A and B at 80 and 140 kVp.

WALINET: A water and lipid identification convolutional neural network for nuisance signal removal in MR spectroscopic imaging.

Purpose: Proton magnetic resonance spectroscopic imaging ( -MRSI) provides noninvasive spectral-spatial mapping of metabolism. However, long-standing problems in whole-brain -MRSI are spectral overlap of metabolite peaks with large lipid signal from scalp, and overwhelming water signal that distorts spectra. Fast and effective methods are needed for high-resolution -MRSI to accurately remove lipid and water signals while preserving the metabolite signal.

Improved phosphorus MRSI acquisition through compressed sensing acceleration combined with low-rank reconstruction.

Objectives: Phosphorus-31 magnetic resonance spectroscopic imaging (P-MRSI) is a non-invasive tool for assessing cellular high-energy metabolism in-vivo. However, its acquisition suffers from a low sensitivity, which necessitates large voxel sizes or multiple averages to achieve an acceptable signal-to-noise ratio (SNR), resulting in long scan times.

Materials And Methods: To overcome these limitations, we propose an acquisition and reconstruction scheme for FID-MRSI sequences.

Fast High-Resolution Metabolite Mapping in the rat Brain Using H-FID-MRSI at 14.1 T.

Magnetic resonance spectroscopic imaging (MRSI) enables the simultaneous noninvasive acquisition of MR spectra from multiple spatial locations inside the brain. Although H-MRSI is increasingly used in the human brain, it is not yet widely applied in the preclinical setting, mostly because of difficulties specifically related to very small nominal voxel size in the rat brain and low concentration of brain metabolites, resulting in low signal-to-noise ratio (SNR). In this context, we implemented a free induction decay H-MRSI sequence (H-FID-MRSI) in the rat brain at 14.