Publications by authors named "A S Kirthi Koushik"
Article Synopsis
- The study focused on high-grade epithelial ovarian cancer survivors post-chemotherapy, analyzing their sleep quality, duration, efficiency, and insomnia, and how these factors relate to the risk of disease recurrence.
- Out of 97 women surveyed, over half reported poor sleep quality, efficiency, and duration, while a majority did not experience insomnia; these sleep patterns remained consistent after four months.
- The results indicated no significant correlation between sleep characteristics and cancer recurrence overall, but suggested a potential association for fully platinum-sensitive women, highlighting the need for further research with larger groups to clarify these relationships.
Orthopaedic surgeons hold differing opinions on replacing the patella during total knee arthroplasty (TKA) for knee osteoarthritis, sparking a continued discussion on the optimal approach. Patellar resurfacing (PR) replaces the patella's surface with a prosthetic component, aiming to enhance joint function and reduce anterior knee pain. However, it has potential complications such as avascular necrosis, fractures, and patellar clunk syndrome.
View Article and Find Full Text PDFBackground: Proximal humerus fractures are common in elderly patients and are often associated with osteoporosis. The management of these fractures, particularly three-part and four-part fractures, remains controversial, with conservative and surgical treatments both employed. This study compared conservative and surgical management's functional outcomes in subjects over 50 years.
View Article and Find Full Text PDFObjective: To evaluate the association between gestational trophoblastic disease and the subsequent risk of developing non-trophoblastic cancer.
Methods: We conducted a retrospective cohort study of 3084 women with gestational trophoblastic disease and 1 415 812 women with obstetric deliveries in Quebec, Canada, between 1989 and 2021. The main exposure was gestational trophoblastic disease, including hydatidiform moles, invasive moles, and gestational choriocarcinoma.
Article Synopsis
- Excess body fat in older age can increase the risk of ovarian cancer, although the connection is not very strong.
- A study in Montreal analyzed body mass index (BMI) data over decades for women 50 and older to understand different life stages' impact on ovarian cancer risk.
- The findings indicate that the accumulation hypothesis best explains the link between BMI and ovarian cancer risk, particularly highlighting the early childbearing years as a potentially sensitive period for increased risk.