Publications by authors named "A S Holzer"

Article Synopsis
  • All vertebrates, from ancient fishes to mammals, possess adaptive immunity and immunological memory, although the specific responding cells in fish have not been clearly defined.
  • Researchers infected common carp with a cnidarian parasite and observed that B cells proliferated and showed signs of differentiation, indicating they can form memory cells.
  • The study revealed that these memory B cells can persist for at least six months, alongside identifying a distinct population of plasma cells, suggesting that teleost fish possess the necessary immune components for effective long-term disease protection akin to other vertebrates.
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  • - Human herpesvirus-8 (HHV-8), linked to Kaposi's sarcoma (KS), is more prevalent in individuals co-infected with HIV-1, especially in sub-Saharan African men, making it common among this group prior to the HIV-1 epidemic.
  • - Researchers tested 58 HHV-8-positive serum samples for antibodies targeting specific glycoproteins and found that neutralizing capacity increases during KS remission, with heightened antibodies against glycoprotein K8.1 during both active disease and remission.
  • - The study suggests that glycoproteins like gHgL could be key targets for neutralizing antibodies, and recovery from KS might be linked to enhanced neutralizing capacity, indicating a
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  • Foodborne illnesses like listeriosis, caused by the Listeria bacteria, are a big worry for public health, especially during outbreaks.
  • Scientists collected and studied over 1800 Listeria samples from patients in Germany to understand how the bacteria spread and caused infections.
  • They found that many infection clusters lasted a long time and could affect people in different regions, with some bacteria types being more harmful than others.
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Type III secretion system (T3SS) is an important virulence system in Gram-negative bacteria. In this investigation, different environmental conditions that regulate the expression of T3SS genes in Yersinia ruckeri were investigated aimed at obtaining a better understanding about its modulation after various environmental challenges. Four isolates of Y.

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Plant pathogens pose a high risk of yield losses and threaten food security. Technological and scientific advances have improved our understanding of the molecular processes underlying host-pathogen interactions, which paves the way for new strategies in crop disease management beyond the limits of conventional breeding. Cross-family transfer of immune receptor genes is one such strategy that takes advantage of common plant immune signalling pathways to improve disease resistance in crops.

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