Factors affecting women's access to primary care in the United States since the Affordable Care Act: A mixed-methods systematic review.

Background: In the United States, the Affordable Care Act (ACA) expanded public and private health coverage, increased health insurance affordability, reduced healthcare costs, and improved healthcare quality for many. Despite ACA provisions, lack of insurance and other factors continue to affect working-age women's access to primary care services.

Methods: We conducted a mixed-method systematic review to identify factors that affect women's access to primary care services since the ACA.

Engineered Protein Hydrogels as Biomimetic Cellular Scaffolds.

The biochemical and biophysical properties of the extracellular matrix (ECM) play a pivotal role in regulating cellular behaviors such as proliferation, migration, and differentiation. Engineered protein-based hydrogels, with highly tunable multifunctional properties, have the potential to replicate key features of the native ECM. Formed by self-assembly or crosslinking, engineered protein-based hydrogels can induce a range of cell behaviors through bioactive and functional domains incorporated into the polymer backbone.

Cross-cultural comparison of low back pain in the nursing workforce: A pilot study.

Aim: This study aimed to analyse cross-cultural differences in the prevalence of low back pain (LBP) and other back pain of general nurses in direct inpatient care in the Czech Republic (CZ) and Great Britain (GB).

Methods: The survey was used using an extended standardized Nordic Musculoskeletal Questionnaire and self-created additional questions. The data were analysed with Stata 15 using a significance level of 0.

Engineered matrices reveal stiffness-mediated chemoresistance in patient-derived pancreatic cancer organoids.

Pancreatic ductal adenocarcinoma (PDAC) is characterized by its fibrotic and stiff extracellular matrix. However, how the altered cell/extracellular-matrix signalling contributes to the PDAC tumour phenotype has been difficult to dissect. Here we design and engineer matrices that recapitulate the key hallmarks of the PDAC tumour extracellular matrix to address this knowledge gap.

The place for people in rewilding.

Rewilding, although controversial, is increasingly presented as humanity's best hope of addressing the global biodiversity crisis, but it remains unclear how restoring nonhuman autonomy affects people's relationships with nature. We conceptualized 3 human-nature relationships (HNRs) that could occur when restoring nonhuman autonomy: human-nature dichotomy, human-nature compromise, and human-nature mutualism. Through 51 interviews, we then empirically tested the occurrence of these HNRs across diverse actors living and working in 2 longstanding British rewilding initiatives to better understand the place for people in rewilding.