Publications by authors named "A S Foo"

Background: The increasing prevalence of psychological distress among mothers is outpacing the effectiveness of conventional coping methods like cognitive behavioral therapy. The efficacy of alternatives such as writing therapy for maternal psychological well-being remains uncertain due to a lack of extensive research and inconsistent findings.

Objective: The aim of this study was to evaluate the effectiveness of expressive writing therapy in comparison to standard postpartum care for alleviating psychological distress, encompassing symptoms of depression, anxiety, or stress, in postpartum women.

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  • * This research created the Mosquito-Associated Isolate Collection (MosAIC) with 392 bacterial isolates and their genomic data to provide more detailed information than previous studies, which mainly relied on basic genetic markers.
  • * The study also analyzed specific bacterial genera and discovered gene clusters linked to mosquito host interactions, paving the way for future research on how these bacteria affect mosquito behavior and disease transmission.
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  • - We conducted a comprehensive review of studies from 1990 to 2021 to explore how socioeconomic factors influence higher health burdens and outcomes in diseases where self-care plays a key role in treatment and prevention.
  • - The review examined 42 diseases across categories like cardiovascular, nutritional, digestive, and respiratory disorders, utilizing data from over-the-counter medicine sales to identify relevant literature.
  • - Results indicated that lifestyle factors, as well as socioeconomic determinants such as education and income, were significant risk factors, although no clear link was found between these factors and the prevalence of self-medication.
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The cockroach allergen Bla g 1 encloses an exceptionally large hydrophobic cavity, which allows it to bind and deliver unsaturated fatty acid ligands. Bla g 1-mediated delivery of naturally occurring (nMix) ligands has been shown to destabilize lipid membranes, contributing to its digestive/antiviral functions within the source organism. However, the consequences of this activity on Bla g 1 allergenicity following human exposure remain unknown.

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Optimizing catalysts through high-throughput screening for asymmetric catalysis is challenging due to the difficulty associated with assembling a library of catalyst analogues in a timely fashion. Here, we repurpose DNA excision repair and integrate it with bioorthogonal conjugation to construct a diverse array of DNA hybrid catalysts for highly accessible and high-throughput asymmetric DNA catalysis, enabling a dramatically expedited catalyst optimization process, superior reactivity and selectivity, as well as the first atroposelective DNA catalysis. The bioorthogonality of this conjugation strategy ensures exceptional tolerance toward diverse functional groups, thereby facilitating the facile construction of 44 DNA hybrid catalysts bearing various unprotected functional groups.

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