Genetic Markers as Risk Factors for the Development of Impulsive-Compulsive Behaviors in Patients with Parkinson's Disease Receiving Dopaminergic Therapy.

Impulsive-compulsive and related behavioral disorders (ICD) are drug-induced non-motor symptoms of Parkinson's disease (PD). Recently research has focused on evaluating whether ICD could be predicted and managed using a pharmacogenetic approach based on dopaminergic therapies, which are the main risk factors. The aim of our study was to evaluate the role of candidate genes such as , , , , , , , , gene polymorphisms in the pathogenesis of ICD in PD.

Fungal Planet description sheets: 1042-1111.

Novel species of fungi described in this study include those from various countries as follows: , from marine sediment sand. , (incl. gen.

Towards an understanding of the genus with emphasis on the species complex (, ).

is one of the earth tongue genera with viscid or glutinous ascocarps. Based on morphology and ITS1-5.8S-ITS2, nrLSU and sequence data, seven new species are described: , , , , , , and .

[A clinical and genetic study of impulsive-compulsive disorders in patients with Parkinson's disease].

Aim: To evaluate the frequency and spectrum of impulsive-compulsive disorders (ICDs) in patients with Parkinson's disease (PD) without dopaminergic medication and among patients receiving dopaminergic replacement therapy, depending on personality type, genetic factors, and to determine the influence of ICDs on the development of other non-motor manifestations of the disease.

Material And Methods: Three hundred and eighty-six consecutive patients with idiopathic PD, including untreated patients with PD (de novo) and patients receiving dopaminergic replacement therapy during one year, were examined. ICDs were evaluated with QUIP and diagnostic criteria.