Genotyping-by-sequencing uncovers a Thinopyrum 4StS·1JS Robertsonian translocation linked to multiple stress tolerances in bread wheat.

GBS read coverage analysis identified a Robertsonian chromosome from two Thinopyrum subgenomes in wheat, conferring leaf and stripe rust resistance, drought tolerance, and maintaining yield stability. Agropyron glael (GLAEL), a Thinopyrum intermedium × Th. ponticum hybrid, serves as a valuable genetic resource for wheat improvement.

Particularities of deposition of two ICS-LABA fixed dose combination dry powder aerosol drugs in the airways of COPD patients.

The aim of this study was to analyse the effect of breathing parameters, age, gender and disease status on the lung doses of the two ICS + LABA fixed combination dry powder drugs. Breathing parameters of 113 COPD patients were measured while inhaling through emptied NEXThaler® and Ellipta® inhalers and the corresponding lung doses were calculated. Lung dose of Foster® NEXThaler® was superior to the lung dose of Relvar® Ellipta® in around 85 % of the patients.

The role of cognitive motivation and self-regulation in coping with occupational demands.

Cognitive motivation (COM) in conjunction with self-regulation (SR) was demonstrated to be positively linked to mental health in educational and clinical contexts. We introduce COM and SR in the occupational context and hypothesize these traits-based on their conceptual link to hardiness - to counteract health-risking stressors. Data from two large cross-sectional studies in Germany comprise a sample of 1,022 psychosomatic rehabilitation in-patients and a healthy sample of 298 employees of various occupations.

High throughput in-line content uniformity measurement of tablets based on real-time UV imaging.

This paper presents a precursor of a novel, high-throughput, in-line system, which utilizes ultraviolet (UV) imaging in order to predict the active pharmaceutical ingredient (API) content of tablets in real-time, non-destructive manner. Pimobendan, cardiovascular drug used in veterinary medicine was chosen as a fluorescent model API. Two experiments were carried out using different measurement setups, where the tablets were moving at different speeds.

Efficacy of 0.2% povidone-iodine and 0.1% polyhexamethylene biguanide as preoperative antiseptics in equine ophthalmic procedures.

Objective: This retrospective study evaluates the efficacy of povidone-iodine (PI) and polyhexamethylene biguanide (PHMB) as preoperative antiseptics in equine ophthalmic procedures.

Animals Studied: Horses that underwent routine ophthalmic surgery and procedures.

Procedures: Data were collected retrospectively from the medical records of equine patients undergoing ophthalmic procedures.