Publications by authors named "A S Dillies"
Compared Burden of Psoriasis, Atopic Dermatitis, Hidradenitis Suppurativa, and Chronic Urticaria: Baseline Characteristics of the Patients Included in the OMCCI Cohort - A French, Prospective Multicenter Study of Chronic Inflammatory Dermatoses.
Dermatology
December 2024
Introduction: Chronic inflammatory dermatoses (CIDs) can significantly affect patients' lives. The Observatory of Chronic Inflammatory Skin Diseases (OMCCI) cohort was initiated to quantify the impact and disease evolution of four CID over 4 years' follow-up; at least 1,000 patients per CID are planned to be enrolled. The objective of this study was to present baseline characteristics of patients included in the OMCCI cohort between December 2020 and September 2022.
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- Calcific uremic arteriolopathy (CUA) is a serious condition mainly affecting patients with end-stage renal disease (ESRD) on dialysis, marked by calcium deposits in the skin.
- A study compared the elastic fiber structure and skin calcifications in 14 ESRD patients with CUA to 12 without using advanced imaging techniques.
- The findings revealed significant differences in elastic fiber fragmentation and the presence of massive circumferential vascular calcifications in CUA patients, suggesting these features might indicate a more specific link to CUA compared to general calcifications seen in other ESRD patients.
Article Synopsis
- - Acquired hemophagocytic lymphohistiocytosis (HLH) is a serious condition caused by an overactive immune response, often linked to infections, cancers, autoimmune diseases, and recently, immune checkpoint inhibitors (ICIs) used in cancer treatment.
- - A study analyzed 190 HLH cases related to ICI therapy, finding that most patients were older men, with HLH typically appearing about 102 days post-treatment initiation, particularly with medications like nivolumab and pembrolizumab.
- - Results showed HLH occurrences were significantly higher with ICIs compared to other drugs, leading to serious conditions in patients, with a 15.3% mortality rate, highlighting the need for clinicians to be vigilant for
Background: The rate of toxic deaths related to induction chemotherapy in the treatment of locally advanced head and neck cancers is unacceptable and calls into question this therapeutic strategy, which is however highly effective in terms of rate and speed of response. The purpose of the study was to investigate predictive factors of toxicity of induction chemotherapy with docetaxel, cisplatin, and 5-fluorouracil (TPF) in locally advanced head and neck cancers (LAHNC).
Methods: Between June 2009 and December 2017, 113 patients treated consecutively with TPF were included retrospectively.