Age-Related Ventricular Tachycardia Substrate Characteristics for Repaired Tetralogy of Fallot Before Transcatheter Pulmonary Valve Placement.

Background: Ventricular tachycardia (VT) substrate characteristics before transcatheter pulmonary valve replacement (TPVR) in repaired tetralogy of Fallot (rTOF) are unknown.

Objectives: In this study, the authors sought to evaluate substrates for sustained monomorphic VT before TPVR in rTOF.

Methods: Retrospective (2017 to 2021) and prospective (commencing 2021) rTOF patients with native right ventricular outflow tract referred for electrophysiology study (EPS) before TPVR were included.

Reanalysis of Exome Sequencing Data in the Indian Undiagnosed Diseases Program: Improving Diagnostic Yield and Ending Diagnostic Odyssey.

In 2021, the Indian Undiagnosed Diseases Program was initiated for patients without a definite diagnosis despite extensive evaluation in four participating sites. Between February 2021 and March 2023, a total of 88 patients were recruited and underwent deep phenotyping. A uniform methodology for data re-analysis was implemented as the first step prior to conducting additional genomic testing.

Randomized comparison of precut papillotomy and endosonography guided rendezvous procedure for difficult biliary access in Malignant distal biliary obstruction.

Background And Aims: Difficult biliary cannulation (DBC) is a marker for prolonged procedure time and increased adverse event rate (AER) during endoscopic retrograde cholangiopancreatography (ERCP). We previously showed that EUS-guided rendezvous procedure (EUS-RV) had a higher single session success rate than precut papillotomy (PcP) in DBC patients. The present randomized study aims at comparing the technical success and AER between the two approaches.

A fluorometric sensor for Tin(II) detection using Azomethine-Triazole organosilane: Turn-off mechanism, antioxidant activity and molecular docking insights.

The need for metal ion sensors is increasing daily due to the harmful impact of metal ions on human health, the environment, and the aquatic ecosystem. The present study highlights synthesizing an azomethine functionalized triazole allied organosilane (5a) probe as a turn-off fluorometric sensor for Sn(II) recognition with high anti-interference even when the other metal ions are present. The probe (5a) offers a detection limit of up to 6.

Bridge Radius Evolution during Coalescence of Ferrofluid Droplets Suspended in a Nonmagnetic Outer Fluid.

Understanding the droplet coalescence/merging is vital for many areas of microfluidics such as biochemical reactors, drug delivery, inkjet printing, oil recovery, etc. In the present study, we carried out numerical simulations of two magnetic droplets suspended in a nonmagnetic fluid matrix and coalescing under the influence of an external magnetic field. We observed that the applied magnetic field played a key role in the merging dynamics of the magnetic droplets.