Publications by authors named "A S Cousin"

Background: Quantification of Amyloid beta (Aβ) oligomers in plasma enables early diagnosis of Alzheimer's Disease (AD) and improves our understanding of underlying pathologies. However, quantification necessitates an extremely sensitive and selective technology because of very low Aβ oligomer concentrations and possible interference from matrix components.

Methods: In this report, we developed and validated a surface-based fluorescence distribution analysis (sFIDA) assay for quantification of Aβ oligomers in plasma.

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  • * This research marks the first discovery of kaolinite or halloysite on another planet, alongside findings of dehydrated minerals indicating possible intense alteration processes.
  • * The rocks' formation likely resulted from intense water activity followed by heating and dehydration, possibly linked to impact events that dispersed the materials across the crater.
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  • The study explores the unique foam behavior of dissolved phosphogypsum from phosphate fertilizer factories in Gabes, Tunisia, focusing on its formation and environmental impact.
  • Researchers identified the foam as an unstable mixture that forms through a series of steps involving dissolution, stabilization by surfactants, and eventual breakdown due to environmental factors.
  • The findings highlight PGF's capacity to carry and spread toxic radiochemical contaminants in marine settings, urging the need to prevent untreated waste discharge into coastal areas to mitigate health and environmental risks.
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Introduction: Long-term enophthalmos and diplopia resulting from orbital bone loss pose significant challenges in reconstructive surgery. This study evaluated the effectiveness of patient-specific porous titanium implants (PSIs) for addressing these conditions.

Materials And Methods: This retrospective study involved 12 patients treated at Croix-Rousse Hospital, Lyon, from April 2015 to April 2022 who underwent late reconstruction via PSI for unilateral complex orbital bone loss.

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The purpose of the study was to determine whether the duration of preoperative pain affects outcomes of temporomandibular joint replacement (TMJR). Twenty-seven patients who underwent primary TMJR between 1 July 2020 and 31 October 2022 were retrospectively assessed for duration of preoperative pain, level of preoperative and postoperative pain on a visual analogue scale (VAS; 0, none; 10, severe), preoperative and postoperative range of motion (ROM), and net change in quality of life (much better, better, same, worse, much worse), reporting the longest available follow up for each patient. Surgical success was defined as postoperative pain of ≤4 and postoperative ROM of ≥30 mm, or net change (Δ) in ROM of ≥10 mm.

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