Publications by authors named "A S Borggreve"

Occult metastases are detected in 10-15% of patients during exploratory laparotomy for pancreatic cancer. This study developed and externally validated a model to predict occult metastases in patients with potentially resectable pancreatic cancer. Model development was performed within the Dutch Pancreatic Cancer Audit, including all patients operated for pancreatic cancer (January 2013-December 2017).

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Background And Purpose: Diffusion weighted magnetic resonance imaging (DW-MRI) can be prognostic for response to neoadjuvant chemotherapy (nCRT) in patients with esophageal cancer. However, manual tumor delineation is labor intensive and subjective. Furthermore, noise in DW-MRI images will propagate into the corresponding apparent diffusion coefficient (ADC) signal.

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Article Synopsis
  • - Anastomotic leakage (AL) is a serious complication following esophagectomy, and ischemic conditioning (ISCON) of the stomach may decrease its occurrence when performed 14 days prior to surgery.
  • - A multicenter trial assessed the safety and feasibility of laparoscopic ISCON in patients with esophageal cancer who are at high risk for AL, showing that the procedure had no major complications and a short hospital stay.
  • - Of the 20 patients treated, AL occurred in just 15%, and no mortality was observed within 90 days post-surgery; further research is needed to confirm whether ISCON significantly lowers AL rates.
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Introduction: The balance between potential oncological merits and surgical risks is unclear for the additional step of performing paratracheal lymphadenectomy during esophagectomy for cancer. This study aimed to investigate the impact of paratracheal lymphadenectomy on lymph node yield and short-term outcomes in patients who underwent this procedure in the Netherlands.

Methods: Patients who underwent neoadjuvant chemoradiotherapy followed by transthoracic esophagectomy were included from the Dutch Upper Gastrointestinal Cancer Audit (DUCA).

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Background: Anastomotic leakage is the most important surgical complication following esophagectomy. A major cause of leakage is ischemia of the gastric tube that is used for reconstruction of the gastrointestinal tract. Generalized cardiovascular disease, expressed by calcifications of the aorta and celiac axis stenosis on a pre-operative CT scan, is associated with an increased risk of anastomotic leakage.

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