Sonographic Assessment of Splenic Manifestations in Sickle Cell Disease Patients and Its Relation to Hematological Parameters: A Cross-Sectional Study in Basra, Iraq.

Background Hemoglobinopathies, such as sickle cell disease (SCD), are inherited disorders of hemoglobin (Hb) synthesis. SCD presents with complex clinical manifestations, including anemia, painful episodes, and organ damage due to recurrent vaso-occlusion. The spleen is one of the first organs affected in SCD patients, with hyposplenism typically occurring by age five.

Clinical whole Exome Sequencing Reveals Novel Homozygous Missense Variant in the Gene causing Autosomal Recessive Spinocerebellar Ataxia.

Background & Objective: Autosomal recessive cerebellar ataxias (ARCA) are rare heterogenous neurodegenerative disorders characterized by degeneration of the cerebellum and spinal cord with an early onset before the age of 20 years. PMPCA (MIM: 613036), is a key enzyme in mitochondrial protein processing which is critical for cell survival and growth. Our objective was to investigate Peptidase, Mitochondrial Processing Subunit Alpha (PMPCA) mutations linked with Spinocerebellar ataxia, autosomal recessive 2 (SCAR2).

E-cadherin Single Nucleotide Variants Are Associated with Increasing Susceptibility to Periodontitis.

Objectives:  To investigate the association of single nucleotide polymorphisms (SNPs) with periodontitis and the potential of these SNPs for identifying susceptibility to periodontitis.

Materials And Methods:  Periodontal clinical parameters were recorded followed by collecting venous blood for DNA extraction. Polymerase chain reaction was used to amplify target segments of the gene.

High performance BO/MWCNTs and TiB/MWCNTs nano-adsorbents for the co-sorption of cyanide and phenol from refinery wastewater.

The refinery industry has witnessed tremendous activity aimed at producing petrochemicals for the benefit of the teeming populace. These activities are accompanied by the discharge of wastewater containing chemical substances and elements that have negative impacts on the ecosystem. The presence of phenol and cyanide contaminants in refinery wastewater poses serious health hazards to humans, necessitating their removal.

Microbiological and Salivary Biomarkers Successfully Predict Site-Specific and Whole-Mouth Outcomes of Nonsurgical Periodontal Treatment.

: Nonsurgical periodontal treatment (NSPT) is the gold-standard technique for treating periodontitis. However, an individual's susceptibility or the inadequate removal of subgingival biofilms could lead to unfavorable responses to NSPT. This study aimed to assess the potential of salivary and microbiological biomarkers in predicting the site-specific and whole-mouth outcomes of NSPT.