Publications by authors named "A Rydelius"
Background: Early detection of treatment response is important for the management of patients with malignant brain tumors such as glioblastoma to assure good quality of life in relation to therapeutic efficacy.
Aim: To investigate whether parametric response mapping (PRM) with diffusion MRI may provide prognostic information at an early stage of standard therapy for glioblastoma.
Materials And Methods: This prospective study included 31 patients newly diagnosed with glioblastoma WHO grade IV, planned for primary standard postoperative treatment with radiotherapy 60Gy/30 fractions with concomitant and adjuvant Temozolomide.
Introduction: Secondary tumoral parkinsonism is a rare phenomenon that develops as a direct or indirect result of brain neoplasms or related conditions.
Objectives: The first objective was to explore to what extent brain neoplasms, cavernomas, cysts, paraneoplastic syndromes (PNSs), and oncological treatment methods cause parkinsonism. The second objective was to investigate the effect of dopaminergic therapy on the symptomatology in patients with tumoral parkinsonism.
Background: Tumor-related hyperintensities in high -value diffusion-weighted imaging (DWI) are radiologically important in the workup of gliomas. However, the white matter may also appear as hyperintense, which may conflate interpretation.
Purpose: To investigate whether DWI with spherical b-tensor encoding (STE) can be used to suppress white matter and enhance the conspicuity of glioma hyperintensities unrelated to white matter.
Background: Chemo- and radiotherapy (RT) is standard treatment for patients with high-grade glioma, but may cause side-effects on the patient's cognitive function.
Aim: Use of diffusion tensor imaging (DTI) to investigate the longitudinal changes in normal-appearing brain tissue in glioblastoma patients undergoing modern arc-based RT with volumetric modulated arc therapy (VMAT) or helical tomotherapy.
Materials And Methods: The study included 27 patients newly diagnosed with glioblastoma and planned for VMAT or tomotherapy.
Article Synopsis
- The study investigates the effectiveness of amide proton transfer weighted (APTw) MRI in accurately diagnosing primary brain tumors compared to traditional contrast-enhanced MRI methods.
- Researchers assessed 26 patients' MRI results before surgery, comparing APTw imaging with conventional techniques to evaluate their accuracy in diagnosing high grade gliomas (HGG) and low grade gliomas (LGG).
- Findings showed that APTw MRI significantly improved the pre-surgical diagnosis accuracy, suggesting that APTw could identify misclassified tumors, leading to changes in treatment plans for several patients.