Correction: The longitudinal association between patient empowerment and patient-reported outcomes: What is the direction of effect?

[This corrects the article DOI: 10.1371/journal.pone.

Holter study of heart rate variability in children and adolescents with long QT syndrome.

Objectives: This study aimed to retrospectively assess cardiac autonomic activity in children with LQTS, considering genotype, symptoms, sex, age, and beta-blocker therapy (BB) and compare it to healthy controls.

Methods: Heart rate variability (HRV), using power spectrum analysis, was analyzed in 575 Holter recordings from 116 children with LQTS and in 69 healthy children. The data were categorized into four age-groups and four heart rate (HR) ranges.

Lower bone strength in young patients with Fontan circulation compared to controls.

Objectives: Previous reports indicate bone deficits in patients with Fontan circulation. However, the consequences of these deficits on bone strength and when these changes occur are unclear.

Aim: To compare the tibial bone strength-strain index between young patients (6-19 years) with Fontan circulation and age- and sex-matched controls, and to determine strength-strain-index in subgroups of children (6-12 years) and adolescents (13-19 years) versus controls.

Prevalence and spectrum of infectious and inflammatory dermatologic conditions occurring in pediatric heart transplant patients on a predominantly mTOR-based immune suppressive regimen: A retrospective chart review.

Introduction: Pediatric heart transplant patients are routinely followed in dermatology clinics due to elevated risk of cutaneous malignancy. However, transplant patients may experience other, non-cancer-related dermatologic conditions including skin infections, inflammatory diseases, and drug eruptions that can cause significant medical and psychosocial comorbidity.

Methods: A retrospective chart review of all pediatric heart transplant patients at Mayo Clinic Children's Center in Rochester, MN, was performed to determine the prevalence and spectrum of non-cancer dermatologic conditions.

Cardiac response to water activities in children with Long QT syndrome type 1.

Background: Swimming is a genotype-specific trigger in long QT syndrome type 1 (LQT1).

Objective: To examine the autonomic response to water activities in children and adolescents with LQT1.

Methods: In this cross-sectional study, LQT1 patients were age and sex matched to one healthy control subject.