Publications by authors named "A Rungsipipat"
Background And Aim: Feline lymphomas are categorized based on the location of tumor cells, with anatomical classifications including alimentary, mediastinal, multicentric, and extranodal forms. Accurate diagnosis and classification of feline lymphoma are paramount for enhancing treatment and prognosis. T-cell lymphomas are CD3 positive, while B-cell lymphomas exhibit positive forCD20, CD79α, and paired box 5 (PAX5).
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- Pulmonary hypertension (PH) can occur in dogs as a complication of myxomatous mitral valve disease (MMVD), and this study focused on the role of the vasoactive substance endothelin-1 (ET-1) in this condition.
- Lung and blood samples were taken from 20 client-owned dogs and analyzed for ET-1 and its receptor, with results revealing no significant differences in expression or concentration across various groups (normal, MMVD, and MMVD+PH).
- The findings indicate that ET-1 might not play a key role in the development of PH due to MMVD in dogs, but the study's small sample size suggests that more research is necessary to validate these results.
Cats have the highest incidence of lymphoma among all animal species. Lymphoma accounts for 41% of all malignant tumors in cats and is responsible for 90% of hematopoietic tumors in felines. Biopsies are considered the gold standard for diagnosis.
View Article and Find Full Text PDFCanine multicentric lymphoma (CML) is a prevalent hematopoietic neoplasm that initially responds well to treatment but often relapses due to chemotherapy resistance. Evaluation of treatment response is essential for effective management. Ultrasound (US) can differentiate between benign and lymphomatous lymph nodes (LLNs).
View Article and Find Full Text PDFBackground: The histopathological classification of T-cell lymphoma (TCL) in humans has distinctive mutational genotyping that suggests different lymphomagenesis. A similar concept is assumed to be observed in dogs with different TCL phenotypes.
Objective: This study aimed to identify the previously reported single-nucleotide polymorphisms (SNPs) in both human beings and dogs in canine TCLs and null-cell lymphomas (NCLs) and to design compatible oligonucleotides from each variant based on the multiplex polymerase chain reaction.