2D TiC (MXene) as a novel highly efficient and selective agent for photothermal therapy.

Photothermal therapy (PTT) has shown significant potential for anti-cancer modality. In this report, according to our best knowledge, we explore for the first time TiC-based MXene as a novel, highly efficient and selective agent for photothermal therapy (PTT). TiC superficially modified with PEG was obtained from the layered, commercially available TiAlC MAX phase in the process of etching aluminum layers using concentrated HF, and characterized by scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HREM) as well as X-ray photoelectron spectroscopy for chemical analysis (ESCA-XPS).

In vitro studies on cytotoxicity of delaminated TiC MXene.

MXenes are a novel family of 2D materials, the biological activity of which has been largely unexplored. The present study, for the first time, shows some aspects of the in vitro toxicity of 2D sheets of TiC MXene. The TiAlC MAX phase was used in an expansion and delamination process to obtain TiC material in the form of 2D sheets.