UICC-2002 TNM classification is not suitable for differentiated thyroid cancer in children and adolescents.

Background: Recently the UICC-TNM classification for differentiated thyroid cancer (DTC) was changed neglecting the special circumstances for children affected by the disease. While the 1997 TNM classification grouped tumours View Article and Find Full Text PDF

[Concentration levels of thyroxine binding globulin and thyroxine in the blood of euthyroid children. Reliability and diagnostic value of the T4/TBG quotiens--establishing reference values].

The most important transportprotein for thyroxine (T4) is the thyroxine-binding globulin (TBG). This protein and T4 were determined using the radioimmunoassay method in bloodserum of 443 euthyreotic children. The age-specific analysis showed high TBG and T4 concentrations in the postnatal phase, nearly constancy between 1.

[Study of the concentration of triiodothyronine, thyroxine and thyreotropin in blood serum of euthyroid children (author's transl)].

Concentrations of triiodothyronine, thyroxine and thyreotropin were determined using the radioimmunoassay method in blood serum of 369 (male = 231, female = 138) euthyroid children. Beyond the newborn age no significant difference were found for the triiodothyronine and the thyreotropin concentration. Compilation of the values resulted in a physiological triiodothyronine concentration of 1.

[Pluriglandular insufficiency due to transfusion haemosiderosis in Blackfan-Diamond anaemia (author's transl)].

The article reports on a boy aged 16 1/2 years suffering from transfusion haemosiderosis associated with corticoid-resistant blackfan diamond anaemia. Besides hepatosplenomegalia and cardiomegalia, the course of the disease was mainly determined by the deficient functioning of several endocrine glands. The diagnosis revealed primary hypothyroidism, hypoparathyroidism and partial insufficiency of the pituitary gland.