Publications by authors named "A Rolle"

Background: Cardiopulmonary bypass (CPB) induces profound physiological changes that may alter the pharmacokinetics of methadone. We aimed to describe the pharmacokinetics of an intravenous bolus of methadone racemate in adult patients undergoing heart surgery with CPB.

Methods: We prospectively studied 29 patients aged 45 to 75 years scheduled for cardiac surgery with CPB who received methadone 0.

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Article Synopsis
  • * The study focused on creating a set of expert guidelines for managing difficult airways in critically ill adults, specifically those with physiologically challenging conditions like obesity and pregnancy.
  • * An international group of airway management specialists used the Delphi method, which involved multiple rounds of surveys, to achieve consensus on 53 out of 61 proposed statements regarding best practices.
  • * Key recommendations included forming a robust intubation team, using videolaryngoscopy, optimizing patient conditions before intubation, and carefully monitoring the patient's status post-intubation to improve overall outcomes.
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Tissue morphogenesis remains poorly understood. In plants, a central problem is how the 3D cellular architecture of a developing organ contributes to its final shape. We address this question through a comparative analysis of ovule morphogenesis, taking advantage of the diversity in ovule shape across angiosperms.

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Preserving maximum lung function is a fundamental goal of parenchymal-sparing pulmonary laser surgery. Long-term studies for follow-up of lung function after pulmonary laser metastasectomy are lacking. However, a sufficient postoperative lung function is essential for quality of life and reduces potential postoperative complications.

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Background: Aneurysmal subarachnoid hemorrhage (aSAH) is preferentially treated by prompt endovascular coiling, which is not available in Guadeloupe. Subsequently, patients are transferred to Paris, France mainland, by commercial airplane (6751 km flight) after being managed according to guidelines. This study describes the characteristics, management and outcomes related to these patients.

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