Publications by authors named "A Rognoni"
Background: Transcatheter aortic valve implantation (TAVI) has emerged as an effective and safe treatment for patients with symptomatic aortic stenosis. The indication to TAVI should be agreed upon by a Heart Team, and the procedure should be performed in centers with on-site cardiac surgery. However, TAVI complications requiring emergent cardiac surgery (ECS) have become very rare.
View Article and Find Full Text PDFDrug-coated balloons in high-risk patients and diabetes mellitus: A meta-analysis of 10 studies.
Catheter Cardiovasc Interv
December 2024
Background: Despite the improvements in drug eluting stents (DES) technology, suboptimal results have been observed in certain higher-risk subsets of patients, as in diabetes mellitus (DM). Drug-coated balloons (DCB) could represent an alternative to DES in complex populations and anatomies, as in DM.
Aims: The present meta-analysis aimed at assessing the role of DCBs in patients with diabetes mellitus.
Article Synopsis
- Current guidelines recommend keeping LDL-C levels below 55 mg/100 ml for patients with acute coronary syndromes (ACS), but many patients struggle to reach this target due to poor medication adherence.
- A study analyzed 963 ACS patients, using the Morisky Medication Adherence Scale to categorize them into high adherence (HA) and low adherence (LA) groups, finding that 28.7% had low adherence.
- The results showed that HA patients were significantly more likely to achieve the LDL-C target compared to LA patients, indicating that adherence to lipid-lowering therapy plays a crucial role in reaching cholesterol goals.
Article Synopsis
- Low-dose prasugrel (5 mg) is being evaluated for its effectiveness in elderly patients (≥75 years) with Acute Coronary Syndrome, but its routine use is debated due to safety concerns.
- A study involving 59 elderly patients treated with dual antiplatelet therapy showed that high-on treatment residual platelet reactivity (HRPR) was present in 42.4% of them, with a notable correlation to higher body mass index (BMI), lower vitamin D levels, and nitrate use.
- The study concluded that increased BMI, particularly over 26, is a significant predictor of HRPR in patients taking low-dose prasugrel, highlighting the need for careful consideration of dosing in this demographic.