Publications by authors named "A Rock"
Background: As part of Electrophysiology Predictable and Sustainable Implementation of National Registries (EP PASSION), a multi-stakeholder collaboration between the US Food and Drug Administration (FDA), academic and society partners, and cardiovascular implantable electronic device manufacturers, a 5-year bradycardia lead study transitioned from a traditional post-approval study (PAS) to a real-world data (RWD) approach using a novel method to evaluate chronic cardiac lead complications.
Methods: Lead complications were identified using a combination of diagnosis and procedure codes from 2013 to 2020 fee-for-service Medicare claims data along with BIOTRONIK device registration and Medical Device Reporting data from patients implanted between 2013 and 2015 with a Solia S lead. A proof-of-concept analysis was performed using McNemar's test to compare lead complications reported in the traditional PAS with lead complications identified in the RWD.
Article Synopsis
- * Hrg1 is specifically expressed in mature oligodendrocytes and is co-localized with myelin sheaths, suggesting its significant role in myelination.
- * Hrg1 null mutant mice displayed myelin defects and lower levels of myelin iron, indicating that Hrg1 is essential for maintaining myelin integrity and proper cell differentiation.
The Extended Social Network-Oriented Support Model for Intimate Partner Violence Survivors.
Int J Ment Health Nurs
December 2024
Intimate partner violence (IPV) transcends cultural, social and economic boundaries, affecting countless individuals globally. Recovery for IPV survivors is supported by their social networks, yet the readiness of these networks is often poorly understood. This perspective paper proposes an extension to existing network-oriented IPV support models by integrating a focus on the readiness and well-being of informal supporters towards the goal of enhancing IPV survivor recovery through effective networks.
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- Poker machines are linked to high risks of addiction and problematic gambling, with visual cues like flashing lights activating urges to gamble.
- The study investigated whether positive schizotypy (a personality trait associated with unusual experiences) predicted gambling urges and if certain psychological states (like altered awareness and time sense) influenced this relationship.
- Results showed a strong correlation between positive schizotypy and increased gambling urges, with altered states mediating this connection, highlighting important implications for understanding and addressing gambling behavior.
Importance: While an overwhelming majority of patients diagnosed with cancer express willingness to participate in clinical trials, only a fraction will enroll onto a research protocol.
Objective: To identify critical barriers to trial enrollment to translate findings into actionable practice changes that increase cancer clinical trial enrollment.
Design, Setting, And Participants: This survey study included designated site contacts at oncology practices with teams who were highly involved with the Association of Community Cancer Centers (ACCC) Community Oncology Research Institute (ACORI) clinical trials activities, all American Society of Clinical Oncology (ASCO)-ACCC collaboration pilot sites, and/or sites providing care to at least 25% African American and Hispanic residents.