Publications by authors named "A Rizzello"

Background: Organ injury is a common and severe complication of cardiac surgery that contributes to the majority of deaths. There are no effective treatment or prevention strategies. It has been suggested that innate immune system activation may have a causal role in organ injury.

View Article and Find Full Text PDF

Background: The identification of synovial fluid (SF) biomarkers that could anticipate the diagnosis of osteoarthritis (OA) is gaining increasing importance in orthopaedic clinical practice. This controlled trial aims to assess the differences between the SF proteome of patients affected by severe OA undergoing Total Knee Replacement (TKR) compared to control subjects (i.e.

View Article and Find Full Text PDF

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is often characterized by a life-threatening interstitial pneumonia requiring hospitalization. The aim of this retrospective cohort study is to identify hallmarks of in-hospital mortality in patients affected by Coronavirus Disease 19 (COVID-19). A total of 150 patients admitted for COVID-19 from March to June 2021 to "F.

View Article and Find Full Text PDF
Article Synopsis
  • The study compares endothelial injury in children with Kawasaki Disease (KD), Multisystem Inflammatory Syndrome in Children (MIS-C), and acute COVID-19 (AC19) by measuring circulating endothelial cells (CECs).
  • Results showed higher levels of CECs in KD and AC19 patients compared to those with MIS-C, with KD patients showing an increase in CECs from acute to subacute stages.
  • The findings suggest that CECs may serve as biomarkers of inflammation and endothelial dysfunction in KD and MIS-C, indicating different mechanisms of vascular injury in these conditions, warranting further research.
View Article and Find Full Text PDF

Background: Complete rings or posterior bands are both commonly used during mitral valve repair, but which one ensures the best long-term outcome in patients with Barlow disease is a topic of debate. This study evaluated whether the type of annuloplasty device affects the long-term durability of the repair.

Methods: We selected 296 consecutive patients with severe mitral regurgitation due to Barlow disease who underwent edge-to-edge mitral repair at our institution between 2004 and 2013.

View Article and Find Full Text PDF