Publications by authors named "A Riordan"
Infectious disease physicians in England have been diagnosing and managing occasional cases of viral hemorrhagic fever since 1971, including the United Kingdom's first case of Ebola virus disease in 1976. Specialist isolation facilities to provide safe and effective care have been present since that time. Following the emergence of Middle East respiratory syndrome (MERS) in 2012, and the avian influenza A (H7N9) outbreak in 2013, and the 2014-2016 Ebola virus disease outbreak in West Africa, clinical and public health preparedness and response pathways in England have been strengthened for these types of diseases, now called high-consequence infectious diseases (HCIDs).
View Article and Find Full Text PDFIn many species, social interactions decrease behavioral, hormonal, and neural responses to environmental stressors. While "social buffering" and its mechanisms have received considerable attention in mammals, we know less about the phenomenon in fish. The nonapeptide oxytocin regulates social behavior across vertebrates and plays an important role in social buffering in mammals.
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- The study evaluated the impact of the BioFire FilmArray Meningitis/Encephalitis Panel on managing childhood meningitis at two hospitals in the UK and Ireland, focusing on early diagnosis and treatment efficiency.
- It involved a retrospective analysis of 460 children who underwent lumbar punctures, where the FilmArray identified 12 bacterial infections missed by standard culture methods, highlighting its diagnostic advantage.
- Results showed that children with viral or negative cultures had shorter antibiotic courses and hospital stays with the FilmArray compared to previous practices, indicating improved treatment outcomes.
Article Synopsis
- - The survey aimed to gather comprehensive demographic data on hereditary angioedema (HAE) and acquired C1 inhibitor deficiency in the UK to enhance service planning and patient care.
- - A total of 1152 patients with HAE were identified, with a prevalence of 1:59,000 for HAE-1/2 and 1:734,000 for acquired C1 inhibitor deficiency, revealing significant patient demographics and treatment patterns.
- - Findings showed that 45% of HAE patients were on long-term prophylaxis, primarily using danazol, and a significant number had acute treatment supplies available at home, highlighting the need for improved healthcare services for these conditions.