Publications by authors named "A Ridolfo"
Article Synopsis
- People with HIV (PWH) are more susceptible to atherosclerotic cardiovascular disease (ASCVD), making the management of low-density lipoprotein cholesterol (LDL-C) crucial for prevention.
- A study assessed 1,404 PWH aged 40 and over to determine how well their high LDL-C levels were managed according to European Society of Cardiology guidelines, revealing that a significant number were at high risk for ASCVD.
- Results showed that although many participants were at very high or high risk, LDL-C levels were poorly controlled, and only 37% were receiving appropriate lipid-lowering treatment.
Background: Antiretroviral drug combinations affect dolutegravir trough concentrations. Here, the authors focused on dolutegravir plus booster darunavir antiretroviral regimens to investigate the effect of the booster and/or timing of drug administration on dolutegravir and darunavir plasma trough concentrations.
Methods: This retrospective observational study included consecutive people with HIV (PWH) receiving dolutegravir plus booster darunavir antiretroviral regimens for at least 3 months, with at least one assessment of dolutegravir and darunavir plasma trough concentrations.
Biosponge-Encased Placental Stem Cells for Volumetric Muscle Loss Repair.
Adv Wound Care (New Rochelle)
September 2024
Volumetric muscle loss (VML) leads to permanent muscle mass and functional impairments. While mesenchymal stromal cells (MSCs) and their secreted factors can aid muscle regeneration, MSCs exhibit limited persistence in injured tissue post-transplantation. Human placental-derived stem cells (hPDSCs), sharing surface markers with MSCs, demonstrate superior regenerative potential due to their fetal origin.
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