Publications by authors named "A Riddell"
Aim: Investigate signal intensity of colorectal liver metastases (CRLM) at hepatobiliary phase (HBP) gadoxetate-enhanced MRI at two time points pre- (TP1) and post- chemotherapy (TP2) and association with disease-free survival (DFS) in patients undergoing curative liver resection.
Methods: Retrospective study. Single largest tumours outlined and HBP T1 signal intensity measured, normalised to skeletal muscle at TP1 and TP2.
Background: Acquired haemophilia A (AHA) is an acquired bleeding disorder resulting from autoantibodies against Factor VIII (FVIII). Previous studies have reported differences in FVIII inhibitor kinetics (type I or type II) in AHA compared to severe haemophilia A.
Aim: To characterise inhibitor kinetics in AHA and evaluate the proportions displaying type I, II or indeterminate kinetics.
Introduction: Acute liver failure (ALF) has no effective treatment other than liver transplantation and is commonly caused by paracetamol overdose. New treatments are needed to treat and prevent ALF. Alternatively-activated macrophages (AAMs) can promote resolution of liver necrosis and stimulate hepatocyte proliferation.
View Article and Find Full Text PDFAim: To assess the diagnostic accuracy and inter-reader agreement of a simulated abbreviated gadoxetate liver magnetic resonance imaging (MRI) protocol together with contrast-enhanced computed tomography (CE-CT) against a standard gadoxetate MRI for the detection of colorectal liver metastases at baseline.
Materials And Methods: Three readers independently evaluated two sets of images per patient, recording number and location of metastases and benign lesions. Set 1 comprised T1w, T2w, DWI, multiphase CE-T1w, and hepatobiliary phase (HBP) images (standard).
Article Synopsis
- Symmetric dimethylarginine (SDMA) is a by-product of cellular metabolism linked to endothelial dysfunction and vascular risk, challenging its previously considered inert status.
- The review focuses on SDMA's role in cerebrovascular diseases, particularly ischaemic stroke, examining its impact on factors like nitric oxide signaling, inflammation, and oxidative stress.
- Recent studies indicate a correlation between elevated SDMA levels and poor outcomes in stroke patients, emphasizing the need for further research to understand SDMA's potential as both a marker and mediator of cerebrovascular disease.