Background: Diabetes is a disease affecting over 500 million people globally due to insulin insufficiency or insensitivity. For individuals with type 1 diabetes, pancreatic islet transplantation can help regulate their blood glucose levels. However, the scarcity of cadaveric donor islets limits the number of people that could receive this therapy.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
July 2023
This paper studies the possibility of heart kinetic motion for designing a self-powered intracardiac leadless pacemaker by piezoelectric energy harvesting. A Doppler laser displacement sensor measures in vivo heart kinetic motion. Cantilevered and four-point bending piezoelectric harvesters are studied under the measured in vivo heart kinetic motion.
View Article and Find Full Text PDFUnlabelled: Few studies have examined the differentiation of human embryonic stem cell (hESC)-derived pancreatic endoderm cells (PECs) in different implantation sites. Here, we investigate the influence of implantation site and recipient sex on the differentiation of hESC-derived PECs in vivo. Male and female mice were implanted with 5 × 106 hESC-derived PECs under the kidney capsule, in the gonadal fat pad, or subcutaneously within macroencapsulation (TheraCyte) devices.
View Article and Find Full Text PDFObjectives: Assessment of recuperation and death times of a population inflicted by an epidemic has only been feasible through studying a sample of individuals via time-to-event analysis, which requires identified participants. Therefore, we aimed to introduce an original model to estimate the average recovery/death times of infected population of contagious diseases without the need to undertake survival analysis and just through the data of unidentified infected, recovered and dead cases.
Design: Cross-sectional study.