Publications by authors named "A Rene Geist"
Purpose: While there is limited patient-centred evidence (i.e., evidence that is important for patients and end-users) to inform the use of pharmacologic opioid minimization strategies (i.
View Article and Find Full Text PDFTo improve the understanding of the extraction chemistry of An(iii) and Ln(iii) with N-donor ligands 2,6-bis(5-(-butyl)-1-pyrazol-3-yl)pyridine (C4-BPP) in the presence of 2-bromohexanoic acid was investigated. Extraction studies showed an excellent separation factor of SF ≈ 200 and SF ≈ 60 in comparison with the structurally similar ligand 2,6-bis(5-neopentyl-1-pyrazol-3-yl)pyridine C5-BPP (SF ≈ 100), even though C5-BPP showed significantly higher stability constants. Time-resolved laser fluorescence spectroscopy (TRLFS) studies revealed the formation of the ternary 1 : 1 and 1 : 2 complexes [Eu(C4-BPP) (2-bromohexanoate) ] ( = 1-2) ( and ).
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- Dexmedetomidine is being increasingly used in surgeries involving general anesthesia, but its impact on patient outcomes needs further evaluation.
- A systematic review of 44 randomized controlled trials with nearly 5904 participants indicated that intraoperative dexmedetomidine significantly improved recovery quality after surgery.
- The study found a 99% likelihood of any benefit from its use and an 88% chance of achieving a meaningful improvement in recovery, along with a reduction in chronic pain incidence.
Article Synopsis
- The research focuses on the coordination chemistry of trivalent lanthanide (Ln(III)) and actinide (An(III)) complexes using a specific ligand, 2,6-bis(5-(-butyl)-1-pyrazol-3-yl)pyridine (C4-BPP).
- Time-resolved laser fluorescence spectroscopy (TRLFS) indicated that the complex formation is more favorable for curium (Cm(III)) than europium (Eu(III)), with calculated stability constants (log β') demonstrating this preference.
- NMR measurements showed significant differences in the nitrogen bonding characteristics between americium (Am(III)) and lanthanide complexes, revealing a stronger covalent bond in the