Publications by authors named "A Reid Burks"
Unlabelled: Honey bees are the third most economically important agricultural animal in the world due to their role as pollinators. Honey bee pollination services and all hive duties are performed by female workers, while the male drones have one job to mate and share their genetics with a virgin queen from another colony. Thus, drone fitness is directly tied to queen success and colony survival, yet they have been severely understudied compared to their female counterparts.
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- Peanut allergy treatment options are currently limited, but new methods like epicutaneous immunotherapy (EPIT) are being explored.
- Viaskin™ Peanut, a late-stage EPIT method, uses a patch that allows the skin to absorb allergens without breaking the skin barrier, aiming to build tolerance.
- Clinical studies show that Viaskin Peanut can help desensitize children with peanut allergies while maintaining a good safety profile, with mild reactions that tend to lessen over time.
Background: The development of peanut allergy is due to a combination of genetic and environmental factors, although specific genes have proven difficult to identify. Previously, we reported that peanut-sensitized Collaborative Cross strain CC027/GeniUnc (CC027) mice develop anaphylaxis upon oral challenge to peanut, in contrast to C3H/HeJ (C3H) mice.
Objective: This study aimed to determine the genetic basis of orally induced anaphylaxis to peanut in CC027 mice.
Background: Radial probe endobronchial ultrasound (R-EBUS) is often utilized in guided bronchoscopy for the diagnosis of peripheral pulmonary lesions. R-EBUS probe positioning has been shown to correlate with diagnostic yield, but overall diagnostic yield with this technology has been inconsistent across the published literature. Currently there is no standardization for R-EBUS image interpretation, which may result in variability in grading concentricity of lesions and subsequently procedure performance.
View Article and Find Full Text PDFIntroduction: DBV712 250 µg (also referred to as Viaskin Peanut or peanut patch; Viaskin is a trademark of DBV Technologies) is an innovative approach to epicutaneous immunotherapy (EPIT). The patch-based technology system facilitates peanut protein (allergen) absorption into the intact non-vascularized epidermis to promote desensitization to peanut while limiting systemic allergen exposure.
Areas Covered: Efficacy and safety in children have been evaluated in four completed phase 3 studies.