Preliminary results of targeted sequencing of and in a cohort of breast cancer families: New insight into pathogenic variants in patients and at‑risk relatives.

Breast cancer (BC) is the most commonly diagnosed cancer worldwide and a major health concern in Egypt. There is a known association between pathogenic variants identified in breast cancer susceptibility gene ()1 and 2 and the risk of developing BC. However, the number of studies investigating mutations in and in Egypt remains limited.

Effect of magnetic resonance myelography on the target volume in craniospinal irradiation in children.

Aims: To examine the potential role of magnetic resonance myelography (MRM) in defining the clinical target volume for the spinal field in craniospinal irradiation in children.

Materials And Methods: Of the 42 patients for whom magnetic resonance imaging (MRI) of the spine was carried out, 12 patients had MRM. The width of the cerebrospinal fluid (CSF) with any lateral extension at different levels was measured from the coronal MRM.