Publications by authors named "A Recchia"

Introduction: In the literature, the data about the factors related to the choice of the setting at patient's first palliative care admission visit are scanty. In fact it seems that the choice between home or hospice care is mainly based on the opinions and needs of patients, families and physicians. This study aims to address the association between the clinical factors detected at the first palliative visit in advanced cancer patients and the choice of palliative care setting (i.

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: There is a notable lack of protocols addressing extubation techniques in transoral robotic surgery (TORS) for obstructive sleep apnea (OSA). : This retrospective cohort study enrolled patients who underwent TORS for OSA between March 2015 and December 2021 and were managed with different extubation approaches. The patients were divided into two groups: high-flow nasal cannula (HFNC) therapy and conventional oxygen therapy.

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Article Synopsis
  • Collagen VI, made of three chains encoded by specific genes, is crucial for the extracellular matrix and its defects are linked to muscular diseases like Ullrich congenital muscular dystrophy (UCMD).
  • A CRISPR genome editing strategy was developed to specifically target a harmful deletion in the collagen VI gene, achieving 32% editing efficiency and restoring the protein's secretion in patient fibroblasts.
  • The edited fibroblasts not only improved collagen VI levels but also positively impacted cell interactions, suggesting that CRISPR can effectively address genetic mutations in UCMD.
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Background: The myelin sheath ensures efficient nerve impulse transmission along the axons. Remyelination is a spontaneous process that restores axonal insulation, promoting neuroprotection and recovery after myelin damage. There is an urgent need for new pharmacological approaches to remyelination and to improve the most effective molecules.

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Differentiating between species is relevant in human medicine. toxins might be effective against , a nematode causing relevant human morbidity. Our first objective was to evaluate genomic and MALDI-TOF identification methods for .

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