Publications by authors named "A Rebollar Merino"
Climate classification systems (CCSs) are emerging as essential tools in climate change science for mitigation and adaptation. However, their limitations are often misunderstood by non-specialists. This situation is especially acute when the CCSs are derived from Global Climate Model outputs (GCMs).
View Article and Find Full Text PDFThe document provides a comprehensive overview of the diagnosis, monitoring, and treatment of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) with renal involvement, focusing on granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). It outlines the definitions, clinical presentation, histopathological classification, monitoring strategies, induction and maintenance treatments, as well as special considerations for relapsing, refractory, and frail patients with renal AAV. The document was prepared by the Catalan Group for the Study of Glomerular Diseases (GLOMCAT), which comprises nephrologists with extensive experience in the diagnosis and treatment of AAV patients.
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- Multiple myeloma (MM) is currently incurable, but natural killer (NK) cells show potential as a treatment option due to their role in targeting tumor cells.
- NK cells vary in their characteristics (like surface markers) and effectiveness, with certain subsets being linked to better patient outcomes, especially in relation to disease stages.
- Current MM treatments can influence NK cell behavior, suggesting that combining NK cell enhancements with existing therapies may improve overall treatment effectiveness.
Mechanism for Vipp1 spiral formation, ring biogenesis, and membrane repair.
Nat Struct Mol Biol
November 2024
The ESCRT-III-like protein Vipp1 couples filament polymerization with membrane remodeling. It assembles planar sheets as well as 3D rings and helical polymers, all implicated in mitigating plastid-associated membrane stress. The architecture of Vipp1 planar sheets and helical polymers remains unknown, as do the geometric changes required to transition between polymeric forms.
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- - The new 2023 ACR/EULAR classification criteria for antiphospholipid syndrome (APS) were evaluated in a study involving 93 pregnant women with primary APS, with data collected from 2005 to 2023.
- - Only 25.8% of these patients met the new criteria; those who did were younger and had fewer clinical pregnancies, often experiencing severe placentation issues leading to preterm births.
- - The study found that nearly three-quarters of the women did not meet the new criteria, suggesting that the criteria may overlook many patients suffering from obstetric complications associated with APS.